You can try what Microsoft recommends first:
http://windows.microsoft.com/en-us/windows-vista/Windows-Update-error-80072ee2

When that fails (I meant 'if') try the following:

1. . Download this REG file - http://www.netsec.pro/twiki/pub/Main/WindowsUpdateError80072ee2/AutomaticUpdate-RemoveUseServer.reg
2. . Double-click on it to import the setting.
3. . Restart the Windows Update service.
4. . Try running Windows Updates again.

Or you can manually do it via regedit:

1. . Run RegEdit and browse to the following key:
   HKEY_LOCAL_MACHINE\SOFTWARE\Policies\Microsoft\Windows\WindowsUpdate\AU
2. . On the right, delete this value:
   “UseWUServer”=dword:00000001
   Just right-click on it and select Delete
3. . Close the registry editor and restart the Windows Update service.
4. . Run Windows Updates.

– Main.FredPettis - 2012-06-06